:root{--bg:#0a0e14;--soft:#11161f;--panel:#141b26;--border:#1f2a38;--text:#d4dae3;--dim:#7c8a9e;--accent:#eacd76;--accent2:#d3b17d;--danger:#ff7d7d;--ok:#8faa72;--warn:#d6824f}*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--bg);color:var(--text);font-family:"Space Grotesk",sans-serif;line-height:1.55;min-height:100vh}.container{width:min(1080px,calc(100% - 40px));margin:auto;position:relative}nav{position:sticky;top:0;z-index:5;border-bottom:1px solid var(--border);background:rgba(10,14,20,.88);backdrop-filter:blur(10px)}.nav-inner{height:66px;display:flex;align-items:center;justify-content:space-between}.logo{color:var(--text);font-weight:700;text-decoration:none;font-size:1.12rem}.logo span,h1 span{color:var(--accent)}.nav-context,.eyebrow,.section-label{font:500 .73rem "IBM Plex Mono",monospace;letter-spacing:.08em;text-transform:uppercase;color:var(--accent)}main{padding:76px 0 100px}.tool-header{max-width:780px;margin-bottom:38px}.tool-header h1{font-size:clamp(2.5rem,7vw,4.5rem);line-height:1.04;letter-spacing:-.045em;margin:15px 0 20px}.tool-header>p{color:var(--dim);font-size:1.1rem;max-width:680px;margin:0}.workflow{display:flex;align-items:center;gap:12px;margin-top:34px;font:500 .72rem "IBM Plex Mono",monospace;color:var(--dim);text-transform:uppercase}.workflow-step{display:inline-flex;align-items:center;gap:7px;transition:color .2s ease}.workflow-step b{display:grid;place-items:center;width:25px;height:25px;border:1px solid var(--border);border-radius:50%;font:500 .66rem "IBM Plex Mono",monospace}.workflow-step.current{color:var(--accent)}.workflow-step.current b{border-color:var(--accent);background:rgba(234,205,118,.1);box-shadow:0 0 0 3px rgba(234,205,118,.05)}.workflow-step.completed{color:var(--text)}.workflow-step.completed b{font-size:0;border-color:var(--accent2);background:var(--accent2);color:var(--bg)}.workflow-step.completed b:after{content:"done";font-size:.5rem;font-weight:700}.workflow i{height:1px;width:34px;background:var(--border);transition:background .2s ease}.workflow i.completed{background:var(--accent2)}.panel{background:rgba(20,27,38,.95);border:1px solid var(--border);border-radius:10px;padding:clamp(26px,5vw,46px);box-shadow:0 24px 80px rgba(0,0,0,.2)}h2{font-size:clamp(1.65rem,4vw,2.25rem);line-height:1.2;margin:8px 0 10px}h3{font-size:1.3rem;line-height:1.3;margin:6px 0}.lede,.success-heading p{color:var(--dim);margin:0 0 28px;max-width:720px}.dropzone{border:1px dashed #3b536b;border-radius:8px;min-height:280px;display:flex;flex-direction:column;align-items:center;justify-content:center;text-align:center;padding:32px;cursor:pointer;transition:.2s;background:#0e141d}.dropzone:hover,.dropzone.dragging,.dropzone:focus{border-color:var(--accent);background:#101d24;outline:none}.file-icon{font:500 .72rem "IBM Plex Mono",monospace;color:var(--accent);border:1px solid var(--accent2);padding:12px 10px;margin-bottom:20px;border-radius:6px}.dropzone strong{font-size:1.15rem}.dropzone span{color:var(--dim);font-size:.9rem;margin:5px 0 20px}button{font:600 .9rem "Space Grotesk",sans-serif;border-radius:6px;padding:11px 18px;line-height:1.25;cursor:pointer;transition:.18s}button:not(.well):not(.plate-axis):not(.text-button){min-height:44px}button:disabled{opacity:.5;cursor:default}.primary{border:1px solid var(--accent);background:var(--accent);color:var(--bg)}.primary:not(:disabled):hover{transform:translateY(-1px);box-shadow:0 8px 22px rgba(234,205,118,.2)}.secondary{border:1px solid var(--border);background:transparent;color:var(--text)}.secondary:not(:disabled):hover{border-color:var(--accent);color:var(--accent)}.privacy{display:flex;gap:14px;margin-top:22px;background:#14190e;border:1px solid #2e3823;border-radius:7px;padding:17px 19px}.privacy span{color:var(--ok);font-weight:700}.privacy p{margin:0;color:var(--dim);font-size:.88rem}.privacy strong{color:var(--text)}.upload-status{min-height:24px;color:var(--dim);margin:17px 0 0}.upload-status.working{color:var(--accent)}.upload-status.error{color:var(--danger)}.manual{margin-top:16px;border-left:2px solid var(--danger);padding:8px 14px;color:var(--dim)}.manual strong{color:var(--text)}.manual p{margin:5px 0}.success-heading{display:flex;gap:18px;align-items:flex-start}.success-icon{width:42px;height:42px;border:1px solid #3c4b2c;background:#14190e;color:var(--ok);border-radius:50%;display:grid;place-items:center;font-weight:700;flex:none}.success-heading h2{margin-top:2px}.success-heading p{margin:2px 0}.summary-grid{display:grid;grid-template-columns:repeat(3,1fr);border:1px solid var(--border);border-radius:7px;overflow:hidden;margin:30px 0}.metric{padding:18px;border-right:1px solid var(--border);border-bottom:1px solid var(--border)}.metric:nth-child(3n){border-right:0}.metric:nth-last-child(-n+3){border-bottom:0}.metric dt{font:500 .68rem "IBM Plex Mono",monospace;text-transform:uppercase;letter-spacing:.06em;color:var(--dim)}.metric dd{margin:6px 0 0;font-weight:600;font-size:1.08rem}details{border-bottom:1px solid var(--border);padding-bottom:24px}summary{color:var(--accent);cursor:pointer;font-size:.9rem}details ul{color:var(--dim);font-size:.88rem}.standardized-heading{display:flex;justify-content:space-between;align-items:flex-end;gap:20px;margin:32px 0 14px}.standardized-heading>span{color:var(--dim);font:400 .7rem "IBM Plex Mono",monospace;text-transform:uppercase}.table-wrap{overflow:auto;border:1px solid var(--border);border-radius:7px;max-height:350px}table{border-collapse:collapse;font:400 .74rem "IBM Plex Mono",monospace;white-space:nowrap;width:100%}th,td{text-align:left;padding:10px 12px;border-right:1px solid var(--border);border-bottom:1px solid var(--border)}th{position:sticky;top:0;background:#192331;color:var(--accent);z-index:1}td{color:#b7c1ce}.schema-note{color:var(--dim);font-size:.83rem;margin:12px 0 0}.actions{display:flex;justify-content:flex-end;align-items:center;gap:10px;margin-top:30px}footer{border-top:1px solid var(--border);background:var(--soft);padding:30px 0;color:var(--dim);font-size:.8rem}footer .container{display:flex;justify-content:space-between;gap:20px}footer p{margin:0}[hidden]{display:none!important}@media(max-width:720px){.nav-context{display:none}.summary-grid{grid-template-columns:1fr 1fr}.metric:nth-child(n){border-right:1px solid var(--border);border-bottom:1px solid var(--border)}.metric:nth-child(2n){border-right:0}.metric:last-child{border-bottom:0}.standardized-heading{align-items:flex-start;flex-direction:column;gap:12px}.actions{align-items:stretch;flex-direction:column}.actions button{width:100%}footer .container{flex-direction:column}.workflow{gap:7px}.workflow i{width:18px}}

.plate-heading{display:flex;justify-content:space-between;gap:24px;align-items:flex-start}.plate-summary{display:flex;align-items:center;gap:18px;flex-wrap:wrap;margin:24px 0;padding:14px 18px;border:1px solid var(--border);border-radius:6px;color:var(--dim);font-size:.82rem}.plate-summary strong{color:var(--text);font-size:1rem}.plate-summary span{display:flex;align-items:center;gap:6px}.legend-dot{width:9px;height:9px;border-radius:50%;display:inline-block}.plate-layout{display:grid;grid-template-columns:minmax(0,1fr) 300px;gap:24px;align-items:start}.plate-workspace{min-width:0}.plate-toolbar{display:flex;justify-content:space-between;gap:20px;align-items:center;margin-bottom:12px}.plate-toolbar>div{display:flex;align-items:center;gap:12px}.plate-toolbar span{color:var(--dim);font:400 .72rem "IBM Plex Mono",monospace;max-width:430px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.text-button{border:0;background:transparent;color:var(--accent);padding:5px}.plate-scroll{overflow:auto;padding:4px}.plate-grid{display:grid;grid-template-columns:28px repeat(12,minmax(38px,1fr));gap:7px;min-width:680px;user-select:none}.plate-axis{border:0;background:transparent;color:var(--dim);padding:0;font:500 .68rem "IBM Plex Mono",monospace}.plate-axis:hover{color:var(--accent)}.well{aspect-ratio:1;border-radius:50%;border:1px solid #3a4b60;background:#111b27;color:var(--dim);padding:0;display:grid;place-items:center;font:500 .62rem "IBM Plex Mono",monospace;touch-action:none}.well:hover{border-color:var(--accent);color:var(--text)}.well.selected{border-color:var(--accent);background:var(--accent);color:var(--bg);box-shadow:0 0 0 3px rgba(234,205,118,.14)}.well.assigned:not(.selected){color:var(--text);border-width:2px}.well.unavailable{opacity:.18}.role-sample{--role:#4fd1c5;border-color:var(--role)!important}.role-blank{--role:#e8c66a;border-color:var(--role)!important}.role-control{--role:#a98df0;border-color:var(--role)!important}.role-unused{--role:#657386;border-color:var(--role)!important}.legend-dot.role-sample,.legend-dot.role-blank,.legend-dot.role-control,.legend-dot.role-unused{background:var(--role)}.plate-help{color:var(--dim);font-size:.78rem;margin-top:14px}.assignment-panel{border:1px solid var(--border);border-radius:7px;padding:20px;background:#101720;position:sticky;top:88px}.assignment-panel.inactive{opacity:.58}.assignment-panel form{display:grid;gap:13px;margin-top:16px}.assignment-panel label{display:grid;gap:6px;color:var(--dim);font-size:.78rem}.assignment-panel input,.assignment-panel select{width:100%;border:1px solid var(--border);border-radius:4px;background:var(--bg);color:var(--text);padding:10px 11px;font:400 .88rem "Space Grotesk",sans-serif}.assignment-panel input:focus,.assignment-panel select:focus{outline:1px solid var(--accent);border-color:var(--accent)}.assignment-panel .checkbox{grid-template-columns:18px 1fr;align-items:start}.checkbox input{width:auto;margin-top:3px}.assignment-actions{display:grid;grid-template-columns:1fr 1fr;gap:8px;margin-top:6px}.assignment-actions button{padding:10px}.plate-data{margin-top:34px;border-top:1px solid var(--border);padding-top:8px}.empty-row{text-align:center;color:var(--dim);padding:28px}.schema-note code{color:var(--accent);font-family:"IBM Plex Mono",monospace}@media(max-width:900px){.plate-layout{grid-template-columns:1fr}.assignment-panel{position:static}.plate-heading{flex-direction:column}.plate-heading button{align-self:flex-start}}@media(max-width:600px){.plate-toolbar{align-items:flex-start;flex-direction:column}.plate-toolbar>div{flex-wrap:wrap}.plate-summary{gap:10px}.workflow-step{gap:3px}.workflow-step b{width:22px;height:22px}.workflow{font-size:.62rem}}

/* metadata import and dynamic plate layouts */
.plate-setup{display:grid;grid-template-columns:minmax(230px,.7fr) minmax(360px,1.3fr);gap:18px;margin:26px 0}.setup-card{border:1px solid var(--border);border-radius:7px;background:#101720;padding:20px}.setup-card>label,.setup-card>strong{display:block;margin:10px 0 6px}.setup-card select{width:100%;border:1px solid var(--border);background:var(--bg);color:var(--text);padding:11px;border-radius:4px}.setup-card p{color:var(--dim);font-size:.8rem;margin:7px 0}.import-actions{display:flex;gap:9px;flex-wrap:wrap;margin-top:14px}.metadata-status{margin-top:12px;font-size:.8rem}.metadata-status:empty{display:none}.metadata-status.working{color:var(--accent)}.metadata-status.success{color:var(--ok)}.metadata-status.error{color:var(--danger);border-left:2px solid var(--danger);padding-left:12px}.metadata-status ul{margin:7px 0 0;padding-left:18px;max-height:150px;overflow:auto}.well.no-measurement:not(.selected){opacity:.35;border-style:dashed}.plate-grid .well{min-width:0}.plate-grid[data-size="384"] .well{font-size:.48rem}.plate-grid[data-size="384"]{gap:3px}@media(max-width:760px){.plate-setup{grid-template-columns:1fr}.metadata-import{min-width:0}}
.template-downloads{display:flex;gap:9px;flex-wrap:wrap;margin-top:12px}.csv-role-note{margin-top:12px!important;padding-top:10px;border-top:1px solid var(--border)}.csv-role-note code{font-family:"IBM Plex Mono",monospace;color:var(--accent)}

/* Blank correction */
.correction-options{border:1px solid var(--border);border-radius:7px;padding:18px;margin:24px 0;display:grid;gap:10px}.correction-options legend{padding:0 8px;color:var(--accent);font:500 .72rem "IBM Plex Mono",monospace;text-transform:uppercase}.correction-option{display:grid;grid-template-columns:20px 1fr;gap:10px;align-items:start;padding:13px;border:1px solid var(--border);border-radius:5px;background:#101720;cursor:pointer}.correction-option:has(input:checked){border-color:var(--accent2);background:#102023}.correction-option input{margin-top:4px}.correction-option span{display:grid;gap:3px}.correction-option small{color:var(--dim)}.correction-messages{display:grid;gap:10px;margin:18px 0}.validation-block{border-left:3px solid var(--border);background:#101720;padding:14px 16px;border-radius:4px;color:var(--dim);font-size:.85rem}.validation-block strong{color:var(--text)}.validation-block ul{margin:7px 0 0;padding-left:18px}.validation-block.errors{border-color:var(--danger)}.validation-block.warnings{border-color:var(--warn)}.validation-block.success{border-color:var(--ok);color:var(--ok)}.processing-result{border-top:1px solid var(--border);margin-top:30px;padding-top:8px}

/* Plotting */
.experiment-name-card{border:1px solid var(--border);background:#101720;border-radius:7px;padding:16px 18px;margin:20px 0}.experiment-name-card label{display:grid;gap:6px;font-size:.82rem;color:var(--dim)}.experiment-name-card input{border:1px solid var(--border);background:var(--bg);color:var(--text);padding:11px;border-radius:4px;font:500 1rem "Space Grotesk",sans-serif}.experiment-name-card small{color:var(--dim)}.experiment-name-card code{color:var(--accent)}.plot-layout{display:grid;grid-template-columns:250px minmax(0,1fr);gap:22px;margin-top:24px}.plot-controls{display:grid;gap:14px;align-content:start}.control-block{border:1px solid var(--border);background:#101720;border-radius:6px;padding:15px;display:grid;gap:10px}.control-block>label{display:grid;gap:5px;color:var(--dim);font-size:.78rem}.control-block select{border:1px solid var(--border);background:var(--bg);color:var(--text);padding:9px;border-radius:4px}.filter-list{display:grid;gap:6px;max-height:170px;overflow:auto}.filter-check{display:grid;grid-template-columns:18px 1fr;align-items:center;font-size:.8rem;color:var(--dim)}.plot-workspace{min-width:0}.plot-actions{display:flex;justify-content:flex-end;gap:8px;flex-wrap:wrap;margin-bottom:10px}.growth-plot{height:600px;border:1px solid var(--border);border-radius:7px;overflow:hidden}@media(max-width:820px){.plot-layout{grid-template-columns:1fr}.plot-controls{grid-template-columns:repeat(2,minmax(0,1fr))}.growth-plot{height:480px}}@media(max-width:560px){.plot-controls{grid-template-columns:1fr}.growth-plot{height:420px}}
/* Parameter analysis */
.parameter-warning-row td{color:var(--warn)}.methods-list{display:grid;gap:10px;margin:8px 0 20px;padding-left:22px;color:var(--dim);font-size:.88rem}.methods-list li::marker{color:var(--accent)}.methods-citation{margin-top:28px;padding-top:18px;border-top:1px solid var(--border)}.methods-citation p{margin:8px 0 0}
.workflow{flex-wrap:wrap}.parameter-method-card,.methods-card{border:1px solid var(--border);border-radius:7px;background:#101720;padding:20px;margin-top:24px}.parameter-method-card>div:first-child{display:flex;justify-content:space-between;align-items:center;gap:18px;flex-wrap:wrap}.parameter-method-card>div:first-child strong{color:var(--accent)}.parameter-method-card p{color:var(--dim);font-size:.84rem}.privacy-inline{border-left:3px solid var(--ok);padding:10px 14px;background:#14190e}.parameter-settings{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));border:1px solid var(--border);border-radius:6px;overflow:hidden;margin:16px 0 0}.parameter-settings div{padding:12px;border-right:1px solid var(--border);border-bottom:1px solid var(--border)}.parameter-settings div:nth-child(2n){border-right:0}.parameter-settings div:nth-last-child(-n+2){border-bottom:0}.parameter-settings dt{font:500 .68rem "IBM Plex Mono",monospace;color:var(--dim);text-transform:uppercase}.parameter-settings dd{margin:5px 0 0;font:400 .74rem "IBM Plex Mono",monospace;color:var(--text);overflow-wrap:anywhere}.parameter-stages{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;margin-top:20px}.parameter-stages>div{display:grid;grid-template-columns:30px 1fr;align-items:center;border:1px solid var(--border);background:#101720;border-radius:5px;padding:13px}.parameter-stages b{grid-row:1;color:var(--dim)}.parameter-stages span{display:grid}.parameter-stages small{color:var(--dim)}.parameter-stages [data-state=loading]{border-color:var(--accent)}.parameter-stages [data-state=done]{border-color:var(--accent2)}.parameter-stages [data-state=done] b{color:var(--ok)}.parameter-stages [data-state=error]{border-color:var(--danger)}.parameter-stages [data-state=error] b{color:var(--danger)}#parameter-error{margin-top:18px}#parameter-error pre{white-space:pre-wrap;color:var(--danger);font-size:.75rem}.parameter-table{max-height:430px}.parameter-error-row td{color:var(--danger)}.methods-card{margin-top:30px}.methods-card>p{color:var(--dim);font-size:.88rem}.methods-card .standardized-heading{margin-top:0}@media(max-width:720px){.parameter-settings,.parameter-stages{grid-template-columns:1fr}.parameter-settings div:nth-child(n){border-right:0;border-bottom:1px solid var(--border)}.parameter-settings div:last-child{border-bottom:0}}